When do you give Monofer?
Monofer should only be administered when staff trained to evaluate and manage anaphylactic reactions is immediately available, in an environment where full resuscitation facilities can be assured. Each patient should be observed for adverse effects for at least 30 minutes following each Monofer injection.
How long does it take for Monofer to work?
➢ Some improvement in haemoglobin (Hb) level should be observed after 2 weeks, optimum improvement at 4 weeks.
How long does a Monofer infusion take?
Doses up to 1000 mg must be administered over 20 minutes. Doses exceeding 1000 mg must be administered over 30 minutes or more. Single doses above 1500 mg are not recommended. Monofer should be added to maximum 500 mL sterile 0.9% sodium chloride.
What is the difference between Monofer and ferinject?
With MonoFer®, a total dose iron infusion <20mg/kg can be administered in 30 minutes in contrast to Ferinject® (where the maximum cumulative dose per week is 1000mg) regardless of body weight. This reduces the number of hospital visits required and reduces exposure to iron infusions.
When do you use Ganzoni formula?
It is recommended to use the Ganzoni formula in patients who are likely to require individually adjusted dosing such as patients with anorexia nervosa, cachexia, obesity, pregnancy or anaemia due to bleeding. For a person with a body weight above 35 kg, the iron stores are 500 mg or above.
Should you eat before an iron infusion?
Some basic things you can do to prepare on the day of your infusion include: eat your breakfast and lunch, as there is no need to fast for an iron infusion. take your regular medications. be prepared to have a small IV drip put in your arm or hand.
How soon will I feel better after an iron infusion?
How long after my iron infusion will I start to feel better? Your iron levels will be restored directly right after the infusion, however, it can take up to two weeks before you start to notice a difference and feel better.
What are the side effects of Ferinject?
Like all medicines, Ferinject may cause side effects, although these are not common. Side effects that you may experience include: • headache • constipation • dizziness • diarrhoea • nausea (feeling sick) • high temperature • vomiting • shivering • stomach pain • muscle pain.
When is ferinject prescribed?
Ferinject should only be administered when staff trained to evaluate and manage anaphylactic reactions is immediately available, in an environment where full resuscitation facilities can be assured. The patient should be observed for adverse effects for at least 30 minutes following each Ferinject injection.
How do you calculate iron deficiency?
A patient’s total body iron deficit can be calculated using the Ganzoni formula (total iron dose = [actual body weight × (15-actual Hb)] × 2.4 + iron stores) [32].
How often can a Monofer injection be given?
Monofer may be administered as an intravenous bolus injection up to 500 mg up to three times a week at an administration rate of up to 250 mg iron/minute. It may be administered undiluted or diluted in maximum 20 ml sterile 0.9% sodium chloride.
When to use Monofer for iron deficiency treatment?
Monofer is indicated for the treatment of iron deficiency in the following conditions: • When oral iron preparations are ineffective or cannot be used The diagnosis must be based on laboratory tests. Monitor carefully patients for signs and symptoms of hypersensitivity reactions during and following each administration of Monofer.
What should be the concentration of Monofer for infusion?
Monofer should be infused undiluted or diluted in sterile 0.9% sodium chloride. For stability reasons, Monofer should not be diluted to concentrations less than 1 mg iron/ml (not including the volume of the ferric derisomaltose solution) and never diluted in more than 500 ml. Please refer to section 6.3 and 6.6.
What happens if you put Monofer on your skin?
Incorrect administration of Monofer may cause leakage of the product at the injection site, which may lead to irritation of the skin and potentially long lasting brown discolouration at the site of injection. The administration must be stopped immediately when this occurs.
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