What is the use of Esperal tablet?
Esperal Tablet is a medicine used in the treatment of alcohol addiction. It works by producing interaction with alcohol and thereby causing unpleasant effects like nausea, flushing of the face, headaches. Thus, it discourages the patient from taking alcohol while on this medication.
What will happen if you drink alcohol while taking Antabuse?
Using alcohol, even a small amount, while taking this medication can lead to a reaction that may include flushing, throbbing headache, breathing problems (e.g., shortness of breath, fast breathing), nausea, vomiting, dizziness, extreme tiredness, fainting, fast/irregular heartbeat, or blurred vision.
Does Disulfiram cause diarrhea?
Disulfiram alters the normal metabolism of alcohol by inhibiting the enzyme aldehyde dehydrogenase and increases the levels of the toxic alcohol metabolite acetaldehyde. Clinical manifestations include flushing, tachycardia, hypotension, nausea, vomiting, diarrhea, and headache (Swift, 2007).
Does Disulfiram make you sleepy?
Drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What is the action of disulfiram?
Mechanism of Action Disulfiram irreversibly inhibits aldehyde dehydrogenase (ALDH1A1) by competing with nicotinamide adenine dinucleotide (NAD) at the cysteine residue in the active site of the enzyme. ALDH1A1 is a hepatic enzyme of the major oxidative pathway of alcohol metabolism, converting ethanol to acetaldehyde.
How do you take Dizone?
Dizone Tablet may be taken with or without food. Take this medicine as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment. This medication mustn’t be stopped suddenly without talking to your doctor.
Is there a pill that makes you sick when you drink alcohol?
Disulfiram (Antabuse) changes the way your body breaks down alcohol. If you drink while taking it, you get sick.
Is disulfiram bad for liver?
Importantly, disulfiram is a well established cause of clinically apparent liver injury, which can be severe and even fatal. The estimated incidence of acute liver injury is 1 per 10,000 to 30,000 patient-years of disulfiram treatment.
What are the side effects of Esperal 250mg tablets?
What are the side effects of Esperal 250mg Tablet ? 1 Headache 2 Dizziness 3 Weakness 4 Skin Rash 5 Metallic Taste 6 Restlessness 7 Gastrointestinal Disturbance 8 Tremor
What are the side effects of taking Esperal with phenytoin?
Metronidazole, medicine used in the treatment of infections. Concomitant use of Esperal with this medicine can lead to the appearance of psychosis which is short-term. Phenytoin, medicine used to treat epilepsy. Concomitant use of Esperal with this medicine increases concentration of phenytoin in the blood and may lead to side effects.
When is the best time to take Esperal?
The usual dose is 500 mg ( one Esperal tablet) once a day, in the morning during breakfast. Swallow the tablet whole with a glass of water. Avoid using alcohol because you will experience unpleasant symptoms listed above.
How often should I take Esperal for alcohol dependence?
About Esperal 250mg Tablet. The usual dose in adults for treating alcohol dependence is 500 mg, taken orally once daily for 1-2 weeks. The maintained dose is 250 mg taken once daily. Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person.
