What is quinine sulfate used for?
Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps. Usually idiopathic, these muscle cramps are common, particularly in older patients. Quinine may help by decreasing the excitability of the motor end-plate and increasing the muscle refractory period.
What is the brand name for quinine?
Quinine is available under the following different brand names: Qualaquin.
Why was quinine sulfate taken off the market?
December 13, 2006 — The US Food and Drug Administration (FDA) has ordered the removal of unapproved drug products containing quinine, citing serious safety concerns and deaths associated with their use.
What is another name for quinine sulfate?
QUALAQUIN (quinine sulfate) is an antimalarial drug indicated only for treatment of uncomplicated Plasmodium falciparum malaria.
What is quinine naturally found in?
Quinine is a bitter compound that comes from the bark of the cinchona tree. The tree is most commonly found in South America, Central America, the islands of the Caribbean, and parts of the western coast of Africa. Quinine was originally developed as a medicine to fight malaria.
Is quinine a sulfate?
Quinine sulfate is a cinchona alkaloid chemically described as cinchonan-9-ol, 6′-methoxy-, (8α, 9R)-, sulfate (2:1) (salt), dihydrate with a molecular formula of (C20H24N2O2)2•H2SO4•2H2O and a molecular weight of 782.96.
Which drink has most quinine?
tonic water
What products contain quinine? Today, you can find quinine in some of your favorite beverages, most notably in tonic water. Historically, tonic water contained very high levels of quinine and was extremely bitter, requiring sugar and, at times, gin to improve the flavor profile.
What are side effects of quinine sulfate capsules?
See full prescribing information for QUININE SULFATE CAPSULES. Quinine sulfate use for the treatment or prevention of nocturnal leg cramps may result in serious and life-threatening hematologic reactions, including thrombocytopenia and hemolytic uremic syndrome/thrombotic thrombocytopenic purpura (HUS/TTP).
Can you take quinine sulfate at night for leg cramps?
Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps.
Are there any other drugs besides quinine sulfate?
Many drugs besides quinine may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, mefloquine, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.
What can quinine be used for in medicine?
Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
