Can mercaptopurine cause dizziness?
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing. This is not a complete list of possible side effects.
Is purinethol the same as mercaptopurine?
What is Purinethol and how is it used? Purinethol (mercaptopurine) is used to slow the growth of cancer cells. Purinethol is also used to treat certain types of leukemia.
What is 6 mercaptopurine used for?
MERCAPTOPURINE, 6-MP (mer kap toe PYOOR een) is a chemotherapy drug. It interferes with the growth of cancer cells and can reduce immune system activity. It is used to treat certain types of acute leukemia.
Does 6-MP cause baldness?
Important Information About 6-MP The most important things to know about 6-MP is that it may cause certain side effects, such as hair loss, vomiting, diarrhea, and appetite loss. It should also not be used within two weeks of receiving a live vaccination.
What happens if I stop taking mercaptopurine?
Long term remission However there is a risk of relapsing if you stop taking azathioprine or mercaptopurine. Around 1 in 5 people with Crohn’s and 1 in 10 with Ulcerative Colitis are at risk of relapsing within a year of stopping treatment.
When is the best time to take mercaptopurine?
You can take Mercaptopurine with food or on an empty stomach but the choice of method should be consistent from day to day. You should take your medicine at least 1 hour before or 2 hours after having milk or dairy products.
How long can you stay on mercaptopurine?
Research suggests that for some people azathioprine or mercaptopurine can continue to be effective for at least five years and possibly longer.
What is the mechanism of action of 6-mercaptopurine?
6-MP ribonucleotide inhibits purine nucleotide synthesis and metabolism by inhibiting an enzyme called phosphoribosyl pyrophosphate amidotransferase (PRPP amidotransferase). Since this enzyme is the rate limiting factor for purine synthesis, this alters the synthesis and function of RNA and DNA.
What is the mechanism of action of 6 mercaptopurine?
How do you take 6 MP?
Can 6MP cause liver damage?
Mercaptopurine can also lead to a distinctive acute, clinically apparent liver injury that usually presents with fatigue and jaundice and a cholestatic or mixed pattern of serum enzyme elevations 1 to 6 months after starting therapy, but sometimes later, particularly following an increase in dose.
When should I stop taking mercaptopurine?
Yellowing of the skin and whites of the eyes. If you get such symptoms, you should stop taking Mercaptopurine. Any signs of fever or infection (sore throat, sore mouth or urinary problems) or any unexplained bruising or bleeding.
